Nicolescu, S., Secara, E.C., Jiboc, N.M., & Baban, A. (2024). Oncovox: A randomised controlled trial of a web-based acceptance and commitment therapy for breast cancer patients. Journal of Contextual Behavioral Science, 32, 100729. https://doi.org/10.1016/j.jcbs.2024.100729
Background
iACT interventions can be cost-effective and convenient for providing evidence-based care to breast cancer patients (BCPs).
Objectives
Determining the feasibility, acceptability, and efficacy of Oncovox, a guided iACT intervention designed to improve psychosocial outcomes in BCP undergoing treatment.
Methods
A parallel, two-arm, open-label, randomized controlled trial (RCT) evaluating an 8-module intervention. Participants were randomized to the iACT group (N = 75) or a waitlist group (N = 75). Primary outcomes: Quality of Life (QoL), Behavioral Activation (BA), Symptom Interference (SI) and Reward Noticing (RN). Secondary outcomes: anxiety and depression symptoms and psychological flexibility (PF). Measurements were made pre- and post-intervention, twice during the intervention, and at 1- and 2-month follow-up.
Results
SI, anxiety and depression, and PF improved significantly, with further improvement at follow-up. QoL, BA and RN improved moderately, but only when imputed data were analyzed.
Conclusions
Oncovox has good dissemination potential and could be appropriately implemented in stepped care.
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