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Snapshots of the ACT RCT evidence base

Snapshots of the ACT RCT evidence base (December 2019):

In December 2019 there were 347 published RCTs and thus subject guide was made. Details of each of these studies, along with links to the original research articles, can be found here. You can use it as a snapshop of the relative distribution of randomized ACT studies as of 2019. As of early 2026, there are now 1,450 randomized controlled trials (RCTs) of ACT published in scholarly journals. Thus this is not reliable as a snapshot of the current ACT RCT evidence-base.

It is, of course, the case that evidence from RCTs is only one part of evidence-based intervention, and for some questions and issues it is arguably not the most important. Other pages provide information on meta-analyses, processes of change, mediation, qualitative studies, basic studies, single-case designs, and so on. Mere headcounts do not consider the quality of the evidence, which varies from excellent to poor depending on the specific study. That is one reason meta-analyses are so important since typically they examine research quality and attempt to temper conclusion on that basis.

Area:Number of studies as of Dec 2019
Anxiety37
Various35
Depression35
Pain31
Stress18
Substance Abuse17
Weight Loss/Obesity17
Social Anxiety15
Cancer14
Parenting11
Psychosis9
Smoking8
Couple / Marital Relations8
Obsessive-Compulsive Disorder7
Multiple Sclerosis7
Quality of Life7
Diabetes6
Eating Disorders6
Prevention5
Stigma5
Exercise5
Fibromyalgia4
Sleep4
Training4
Sports Performance4
Dialysis3
Occupational Outcomes3
Procrastination3
Suicide3
Borderline Personality Disorder2
Bowel Diseases2
Epilepsy2
Health Behaviors2
HIV2
Tinnitus2
Trichotillomania2
Aggression1
Asthma1
Attention1
Confidence1
Gambling1
Perfectionism1
Pornography1
Pregnancy1
Psychological Flexibility1
Skill Coaching1
Somatic Syndromes1
Stroke1
Trauma1