Much of the movie can be cast into terms relevant to clinical work with ACT. I often refer to people having an "American Beauty" moment in which they wake up one day and realize how their lack of mindfulness/life momentum has led them very far off-course from a path consistent with their values (like the Kevin Spacey character and others).
ACT Principle: There are numerous illustrations of mindfulness (and lack thereof) and the cost of experiential avoidance in the behaviors and choices of the characters.